Patterns of oligonucleotide sequences in viral and host cell RNA identify mediators of the host innate immune system.

The innate immune response provides a first line of defense against pathogens by targeting generic differential features that are present in foreign organisms but not in the host. These innate responses generate selection forces acting both in pathogens and hosts that further determine their co-evol...

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Bibliographic Details
Main Authors: Benjamin D Greenbaum, Raul Rabadan, Arnold J Levine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2694999?pdf=render