Melatonin Attenuates Diabetic Myocardial Microvascular Injury through Activating the AMPK/SIRT1 Signaling Pathway

Melatonin Attenuates Diabetic Myocardial Microvascular Injury through Activating the AMPK/SIRT1 Signaling Pathway

Cardiac microvascular endothelial cell (CMEC) dysfunction is considered as a major contributor to the cardiovascular complications in diabetes mellitus, with oxidative stress caused by hyperglycemia playing a critical role in the progression of CMEC dysfunction. Melatonin is a kind of hormone well k...

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Bibliographic Details
Main Authors:	Bin Wang, Jinyu Li, Mi Bao, Runji Chen, Haiyan Li, Binger Lu, Meixin Chen, Danmei Huang, Yanmei Zhang, Fenfei Gao, Ganggang Shi
Format:	Article
Language:	English
Published:	Hindawi Limited 2021-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2021/8882130

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