Synthesis of benzamides by microwave assisted ring opening of less reactive dimethylaminobenzylidene oxazolone

This paper presents the synthesis of some benzamide compounds (B1–B10) by microwave-assisted ring opening of 4-(4-dimethylaminobenzylidene)-2-phenyl-5-oxazolone (AZ4). By conventional synthesis involving heating, it was found difficult to obtain ring-opened products, probably due to poor tendency of...

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Main Authors:	Saurabh C. Khadse, Vivekananda A. Chatpalliwar
Format:	Article
Language:	English
Published:	Elsevier 2017-02-01
Series:	Arabian Journal of Chemistry
Subjects:	Benzamide 4-(4-Dimethylaminobenzylidene)-2-phenyl-5-oxazolone Anilines
Online Access:	http://www.sciencedirect.com/science/article/pii/S1878535212003115

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spelling	doaj-048e5a825c38436f932135494186312b2020-11-25T02:24:39ZengElsevierArabian Journal of Chemistry1878-53522017-02-0110S1S859S86310.1016/j.arabjc.2012.12.020Synthesis of benzamides by microwave assisted ring opening of less reactive dimethylaminobenzylidene oxazoloneSaurabh C. Khadse0Vivekananda A. Chatpalliwar1Department of Pharmaceutical Chemistry, R.C. Patel Institute of Pharmaceutical Education and Research, Karvand Naka Shirpur, Dist. Dhule, Maharashtra 425 405, IndiaShri Sureshdada Jain College of Pharmacy, Nemi Nagar, Chandwad, Mumbai-Agra Highway, Dist. Nashik, Maharashtra 423 101, IndiaThis paper presents the synthesis of some benzamide compounds (B1–B10) by microwave-assisted ring opening of 4-(4-dimethylaminobenzylidene)-2-phenyl-5-oxazolone (AZ4). By conventional synthesis involving heating, it was found difficult to obtain ring-opened products, probably due to poor tendency of the carbonyl carbon (C5) of AZ4 to undergo nucleophilic attack by mono/or disubstituted anilines. Microwave assisted reactions were easy to perform, have reduced the reaction time and produced good yields.http://www.sciencedirect.com/science/article/pii/S1878535212003115Benzamide4-(4-Dimethylaminobenzylidene)-2-phenyl-5-oxazoloneAnilines
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Saurabh C. Khadse Vivekananda A. Chatpalliwar
spellingShingle	Saurabh C. Khadse Vivekananda A. Chatpalliwar Synthesis of benzamides by microwave assisted ring opening of less reactive dimethylaminobenzylidene oxazolone Arabian Journal of Chemistry Benzamide 4-(4-Dimethylaminobenzylidene)-2-phenyl-5-oxazolone Anilines
author_facet	Saurabh C. Khadse Vivekananda A. Chatpalliwar
author_sort	Saurabh C. Khadse
title	Synthesis of benzamides by microwave assisted ring opening of less reactive dimethylaminobenzylidene oxazolone
title_short	Synthesis of benzamides by microwave assisted ring opening of less reactive dimethylaminobenzylidene oxazolone
title_full	Synthesis of benzamides by microwave assisted ring opening of less reactive dimethylaminobenzylidene oxazolone
title_fullStr	Synthesis of benzamides by microwave assisted ring opening of less reactive dimethylaminobenzylidene oxazolone
title_full_unstemmed	Synthesis of benzamides by microwave assisted ring opening of less reactive dimethylaminobenzylidene oxazolone
title_sort	synthesis of benzamides by microwave assisted ring opening of less reactive dimethylaminobenzylidene oxazolone
publisher	Elsevier
series	Arabian Journal of Chemistry
issn	1878-5352
publishDate	2017-02-01
description	This paper presents the synthesis of some benzamide compounds (B1–B10) by microwave-assisted ring opening of 4-(4-dimethylaminobenzylidene)-2-phenyl-5-oxazolone (AZ4). By conventional synthesis involving heating, it was found difficult to obtain ring-opened products, probably due to poor tendency of the carbonyl carbon (C5) of AZ4 to undergo nucleophilic attack by mono/or disubstituted anilines. Microwave assisted reactions were easy to perform, have reduced the reaction time and produced good yields.
topic	Benzamide 4-(4-Dimethylaminobenzylidene)-2-phenyl-5-oxazolone Anilines
url	http://www.sciencedirect.com/science/article/pii/S1878535212003115
work_keys_str_mv	AT saurabhckhadse synthesisofbenzamidesbymicrowaveassistedringopeningoflessreactivedimethylaminobenzylideneoxazolone AT vivekanandaachatpalliwar synthesisofbenzamidesbymicrowaveassistedringopeningoflessreactivedimethylaminobenzylideneoxazolone
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Synthesis of benzamides by microwave assisted ring opening of less reactive dimethylaminobenzylidene oxazolone

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