Specific protease mutation patterns are associated with oropharyngeal candidiasis in a New Orleans patient cohort of HIV-infected individuals

HIV-1 protease gene sequences were obtained from peripheral blood, saliva or oral tissues of 35 HIV+ patients using nested amplification and manual sequencing of PCR products. Of the 35 HIV+ patients 9 had clinical oropharyngeal candidiasis (OPC) while 26 did not, and only 4 patients were on proteas...

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Bibliographic Details
Main Authors: Peter J. Hickman, Robertino M. Mera, Janet E. Leigh, Paul L. Fidel Jr, Allen R. Mock, William R. Gallaher, Ronald B. Luftig
Format: Article
Language:English
Published: Universidade Estadual de Campinas 2015-11-01
Series:Brazilian Journal of Oral Sciences
Subjects:
Online Access:https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641746