Mechanical force-driven TNFα endocytosis governs stem cell homeostasis

Mechanical force-driven TNFα endocytosis governs stem cell homeostasis

Abstract Mesenchymal stem cells (MSCs) closely interact with the immune system, and they are known to secrete inflammatory cytokines in response to stress stimuli. The biological function of MSC-derived inflammatory cytokines remains elusive. Here, we reveal that even under physiological conditions,...

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Bibliographic Details
Main Authors: Wenjing Yu, Chider Chen, Xiaoxing Kou, Bingdong Sui, Tingting Yu, Dawei Liu, Runci Wang, Jun Wang, Songtao Shi
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-020-00117-x

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