TRPV1 Activation by Capsaicin Mediates Glucose Oxidation and ATP Production Independent of Insulin Signalling in Mouse Skeletal Muscle Cells

TRPV1 Activation by Capsaicin Mediates Glucose Oxidation and ATP Production Independent of Insulin Signalling in Mouse Skeletal Muscle Cells

Background: Insulin resistance (IR), a key characteristic of type 2 diabetes (T2DM), is manifested by decreased insulin-stimulated glucose transport in target tissues. Emerging research has highlighted transient receptor potential cation channel subfamily V member (TRPV1) activation by capsaicin as...

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Bibliographic Details
Main Authors: Parisa Vahidi Ferdowsi, Kiran D. K. Ahuja, Jeffrey M. Beckett, Stephen Myers
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
capsaicin
TRPV1
CAMKK2
ERK1/2
glucose oxidation
ATP
Online Access:https://www.mdpi.com/2073-4409/10/6/1560

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