Ammonia Affects Astroglial Proliferation in Culture.

Ammonia Affects Astroglial Proliferation in Culture.

Primary cultures of rat astroglial cells were exposed to 1, 3 and 5 mM NH4Cl for up to 10 days. Dose- and time-dependent reductions in cell numbers were seen, plus an increase in the proportion of cells in the S phase. The DNA content was reduced in the treated cells, and BrdU incorporation diminish...

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Bibliographic Details
Main Authors: Guillermo Bodega, Berta Segura, Sergio Ciordia, María Del Carmen Mena, Luis Andrés López-Fernández, María Isabel García, Isabel Trabado, Isabel Suárez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4589356?pdf=render

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