Antiviral Actions of 25-Hydroxycholesterol in Fish Vary With the Virus-Host Combination

Antiviral Actions of 25-Hydroxycholesterol in Fish Vary With the Virus-Host Combination

Cholesterol is essential for building and maintaining cell membranes and is critical for several steps in the replication cycle of viruses, especially for enveloped viruses. In mammalian cells virus infections lead to the accumulation of the oxysterol 25-hydroxycholesterol (25HC), an antiviral facto...

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Bibliographic Details
Main Authors: Mikolaj Adamek, Jonathan Davies, Alexander Beck, Lisa Jordan, Anna M. Becker, Miriam Mojzesz, Krzysztof Rakus, Typhaine Rumiac, Bertrand Collet, Graham Brogden, Keith Way, Sven M. Bergmann, Jun Zou, Dieter Steinhagen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
25-hydroxycholesterol
cyprinid herpesvirus 3
spring viremia of carp virus
type I interferon
common carp
rainbow trout
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.581786/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.581786/full

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