Tumor-Associated Macrophages in Oncolytic Virotherapy: Friend or Foe?

Cancer therapy remains a challenge due to toxicity limitations of chemotherapy and radiation therapy. Oncolytic viruses that selectively replicate and destroy cancer cells are of increasing interest. In addition to direct cell lysis, these vectors stimulate an anti-tumor immune response. A key regul...

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Bibliographic Details
Main Authors: Nicholas L. Denton, Chun-Yu Chen, Thomas R. Scott, Timothy P. Cripe
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Biomedicines
Subjects:
Online Access:http://www.mdpi.com/2227-9059/4/3/13