A genome-wide analysis of promoter-mediated phenotypic noise in Escherichia coli.

Gene expression is subject to random perturbations that lead to fluctuations in the rate of protein production. As a consequence, for any given protein, genetically identical organisms living in a constant environment will contain different amounts of that particular protein, resulting in different...

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Bibliographic Details
Main Authors: Olin K Silander, Nela Nikolic, Alon Zaslaver, Anat Bren, Ilya Kikoin, Uri Alon, Martin Ackermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3261926?pdf=render