Age-Associated Changes in Estrogen Receptor Ratios Correlate with Increased Female Susceptibility to Coxsackievirus B3-Induced Myocarditis

Age-Associated Changes in Estrogen Receptor Ratios Correlate with Increased Female Susceptibility to Coxsackievirus B3-Induced Myocarditis

Sexual bias is a hallmark in various diseases. This review evaluates sexual dimorphism in clinical and experimental coxsackievirus B3 (CVB3) myocarditis, and how sex bias in the experimental disease changes with increased age. Coxsackieviruses are major causes of viral myocarditis, an inflammation o...

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Bibliographic Details
Main Authors:	Andreas Koenig, Iwona Buskiewicz, Sally A. Huber
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-11-01
Series:	Frontiers in Immunology
Subjects:	aging and immunocompetence mouse models T-regulatory cells and innate immunity estrogen receptor alpha estrogen receptor alpha:beta ratios and immune competence sex bias in coxsackievirus B3 myocarditis
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01585/full

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