New concepts in molecular imaging: non-invasive MRI spotting of proteolysis using an Overhauser effect switch.

Proteolysis, involved in many processes in living organisms, is tightly regulated in space and time under physiological conditions. However deregulation can occur with local persistent proteolytic activities, e.g. in inflammation, cystic fibrosis, tumors, or pancreatitis. Furthermore, little is know...

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Bibliographic Details
Main Authors: Philippe Mellet, Philippe Massot, Guillaume Madelin, Sylvain R A Marque, Etienne Harte, Jean-Michel Franconi, Eric Thiaudière
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2671144?pdf=render