“On-The-Spot” Arresting of Chondroitin Sulphate Proteoglycans: Implications for Ovarian Adenocarcinoma Recognition and Intervention

“On-The-Spot” Arresting of Chondroitin Sulphate Proteoglycans: Implications for Ovarian Adenocarcinoma Recognition and Intervention

Ovarian Cancer (OC) is one of the leading causes of cancer-associated death among women. The underlying biochemical cause of OC proliferation is usually attributed to the over-expression of Chondroitin Sulphate Proteoglycans (CSPGs) wherein the CS-E subgroup plays a major role in tumor cell prolifer...

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Bibliographic Details
Main Authors: Priyamvada Pradeep, Yahya E. Choonara, Pradeep Kumar, Viness Pillay
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:International Journal of Molecular Sciences
Subjects:
ovarian cancer
proteoglycans
crosslinked chondroitin sulphate
complexation
tumor proliferation
GD3G7 antibody
anti-VEGF
Online Access:http://www.mdpi.com/1422-0067/17/7/1136

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