Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

Alterations of locus coeruleus signal intensity have been associated with functional changes in health and disease. Here, the authors tested a pre-registered hypothesis on a large number of subjects as part of the Cam-CAN consortium.

Bibliographic Details
Main Authors:	Kathy Y. Liu, Rogier A. Kievit, Kamen A. Tsvetanov, Matthew J. Betts, Emrah Düzel, James B. Rowe, Cam-CAN, Robert Howard, Dorothea Hämmerer
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-04-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-15410-w

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spelling	doaj-043e20a098c94f869f17bdda9fe549e42021-05-11T08:16:20ZengNature Publishing GroupNature Communications2041-17232020-04-011111910.1038/s41467-020-15410-wNoradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differencesKathy Y. Liu0Rogier A. Kievit1Kamen A. Tsvetanov2Matthew J. Betts3Emrah Düzel4James B. Rowe5Cam-CANRobert Howard6Dorothea Hämmerer7Division of Psychiatry, University College LondonMedical Research Council Cognition and Brain Sciences Unit, University of CambridgeCambridge Centre for Ageing and Neuroscience (Cam-CAN), University of Cambridge and MRC Cognition and Brain Sciences UnitGerman Center for Neurodegenerative Diseases (DZNE)German Center for Neurodegenerative Diseases (DZNE)Medical Research Council Cognition and Brain Sciences Unit, University of CambridgeDivision of Psychiatry, University College LondonGerman Center for Neurodegenerative Diseases (DZNE)Alterations of locus coeruleus signal intensity have been associated with functional changes in health and disease. Here, the authors tested a pre-registered hypothesis on a large number of subjects as part of the Cam-CAN consortium.https://doi.org/10.1038/s41467-020-15410-w
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Kathy Y. Liu Rogier A. Kievit Kamen A. Tsvetanov Matthew J. Betts Emrah Düzel James B. Rowe Cam-CAN Robert Howard Dorothea Hämmerer
spellingShingle	Kathy Y. Liu Rogier A. Kievit Kamen A. Tsvetanov Matthew J. Betts Emrah Düzel James B. Rowe Cam-CAN Robert Howard Dorothea Hämmerer Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences Nature Communications
author_facet	Kathy Y. Liu Rogier A. Kievit Kamen A. Tsvetanov Matthew J. Betts Emrah Düzel James B. Rowe Cam-CAN Robert Howard Dorothea Hämmerer
author_sort	Kathy Y. Liu
title	Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences
title_short	Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences
title_full	Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences
title_fullStr	Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences
title_full_unstemmed	Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences
title_sort	noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-04-01
description	Alterations of locus coeruleus signal intensity have been associated with functional changes in health and disease. Here, the authors tested a pre-registered hypothesis on a large number of subjects as part of the Cam-CAN consortium.
url	https://doi.org/10.1038/s41467-020-15410-w
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Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

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