CNCC: an analysis tool to determine genome-wide DNA break end structure at single-nucleotide resolution

Abstract Background DNA double-stranded breaks (DSBs) are potentially deleterious events in a cell. The end structures (blunt, 3′- and 5′-overhangs) at DSB sites contribute to the fate of their repair and provide critical information concerning the consequences of the damage. Therefore, there has be...

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Bibliographic Details
Main Authors: Karol Szlachta, Heather M. Raimer, Laurey D. Comeau, Yuh-Hwa Wang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-019-6436-0