CNCC: an analysis tool to determine genome-wide DNA break end structure at single-nucleotide resolution
Abstract Background DNA double-stranded breaks (DSBs) are potentially deleterious events in a cell. The end structures (blunt, 3′- and 5′-overhangs) at DSB sites contribute to the fate of their repair and provide critical information concerning the consequences of the damage. Therefore, there has be...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12864-019-6436-0 |