Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation
Biocatalysis and metal catalysis often provide complimentary reactivities and selectivities. Here, the authors exploit the regioselectivity of an enzymatic C–H activation followed by palladium catalysed carbon-carbon bond formation in one pot, with membrane compartmentalization used to isolate the t...
Main Authors: | Jonathan Latham, Jean-Marc Henry, Humera H. Sharif, Binuraj R. K. Menon, Sarah A. Shepherd, Michael F. Greaney, Jason Micklefield |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11873 |
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