Matrix Gla Protein Promotes the Bone Formation by Up-Regulating Wnt/β-Catenin Signaling Pathway

Matrix Gla Protein Promotes the Bone Formation by Up-Regulating Wnt/β-Catenin Signaling Pathway

Objective: Studies suggest that matrix Gla protein (MGP) is associated with osteoporosis. However, the precise mechanism through which MGP regulates bone metabolism is not fully understood. The purpose of this study was to clarify the role of MGP in bone metabolism.Methods: The MGP gene in MG63 cell...

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Bibliographic Details
Main Authors: Jie Zhang, Zhenrong Ma, Kang Yan, Yong Wang, Ya Yang, Xiang Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Endocrinology
Subjects:
MGP
osteoblast
bone formation
Wnt/β-catenin signaling pathway
osteoporosis
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00891/full

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