Misleading hepatitis B testing in the setting of intravenous immunoglobulin [v1; ref status: indexed, http://f1000r.es/25r]

Intravenous immunoglobulin (IVIG) is commonly used for a wide range of diagnoses, by multiple pediatric subspecialists. We report two cases of hepatitis B screening results post IVIG infusion, where positive anti-Hepatitis B core antigen serology tests indicated possible occult hepatitis infection,...

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Main Authors: Christelle M Ilboudo, Erin M Guest, Angela M Ferguson, Uttam Garg, Mary Anne Jackson
Format: Article
Language:English
Published: F1000 Research Ltd 2013-11-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/2-249/v1
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spelling doaj-041027eff4ee4d959f283ec935e1bf3f2020-11-25T03:18:29ZengF1000 Research LtdF1000Research2046-14022013-11-01210.12688/f1000research.2-249.v12799Misleading hepatitis B testing in the setting of intravenous immunoglobulin [v1; ref status: indexed, http://f1000r.es/25r]Christelle M Ilboudo0Erin M Guest1Angela M Ferguson2Uttam Garg3Mary Anne Jackson4Children’s Mercy Hospitals and Clinics, Division of Infectious Diseases and University of Missouri-Kansas City School of Medicine, Kansas City, MO, 64108, USAChildren’s Mercy Hospitals and Clinics, Department of Pediatrics, Division of Hematology Oncology and University of Missouri-Kansas City School of Medicine, Kansas City, MO, 64108, USAChildren’s Mercy Hospital and Clinics, Department of Pathology and Laboratory Medicine, Division of Laboratory Medicine and University of Missouri-Kansas City School of Medicine, Kansas City, MO, 64108, USAChildren’s Mercy Hospital and Clinics, Department of Pathology and Laboratory Medicine, Division of Laboratory Medicine and University of Missouri-Kansas City School of Medicine, Kansas City, MO, 64108, USAChildren’s Mercy Hospitals and Clinics, Division of Infectious Diseases and University of Missouri-Kansas City School of Medicine, Kansas City, MO, 64108, USAIntravenous immunoglobulin (IVIG) is commonly used for a wide range of diagnoses, by multiple pediatric subspecialists. We report two cases of hepatitis B screening results post IVIG infusion, where positive anti-Hepatitis B core antigen serology tests indicated possible occult hepatitis infection, leading to a delay in care. However, serial antibody testing showed results consistent with the passive transfer of antibodies.http://f1000research.com/articles/2-249/v1Nosocomial & Healthcare-Associated InfectionsPediatric Infectious DiseasesViral Infections (without HIV)
collection DOAJ
language English
format Article
sources DOAJ
author Christelle M Ilboudo
Erin M Guest
Angela M Ferguson
Uttam Garg
Mary Anne Jackson
spellingShingle Christelle M Ilboudo
Erin M Guest
Angela M Ferguson
Uttam Garg
Mary Anne Jackson
Misleading hepatitis B testing in the setting of intravenous immunoglobulin [v1; ref status: indexed, http://f1000r.es/25r]
F1000Research
Nosocomial & Healthcare-Associated Infections
Pediatric Infectious Diseases
Viral Infections (without HIV)
author_facet Christelle M Ilboudo
Erin M Guest
Angela M Ferguson
Uttam Garg
Mary Anne Jackson
author_sort Christelle M Ilboudo
title Misleading hepatitis B testing in the setting of intravenous immunoglobulin [v1; ref status: indexed, http://f1000r.es/25r]
title_short Misleading hepatitis B testing in the setting of intravenous immunoglobulin [v1; ref status: indexed, http://f1000r.es/25r]
title_full Misleading hepatitis B testing in the setting of intravenous immunoglobulin [v1; ref status: indexed, http://f1000r.es/25r]
title_fullStr Misleading hepatitis B testing in the setting of intravenous immunoglobulin [v1; ref status: indexed, http://f1000r.es/25r]
title_full_unstemmed Misleading hepatitis B testing in the setting of intravenous immunoglobulin [v1; ref status: indexed, http://f1000r.es/25r]
title_sort misleading hepatitis b testing in the setting of intravenous immunoglobulin [v1; ref status: indexed, http://f1000r.es/25r]
publisher F1000 Research Ltd
series F1000Research
issn 2046-1402
publishDate 2013-11-01
description Intravenous immunoglobulin (IVIG) is commonly used for a wide range of diagnoses, by multiple pediatric subspecialists. We report two cases of hepatitis B screening results post IVIG infusion, where positive anti-Hepatitis B core antigen serology tests indicated possible occult hepatitis infection, leading to a delay in care. However, serial antibody testing showed results consistent with the passive transfer of antibodies.
topic Nosocomial & Healthcare-Associated Infections
Pediatric Infectious Diseases
Viral Infections (without HIV)
url http://f1000research.com/articles/2-249/v1
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