A new look at auranofin, dextromethorphan and rosiglitazone for reduction of glia-mediated inflammation in neurodegenerative diseases

A new look at auranofin, dextromethorphan and rosiglitazone for reduction of glia-mediated inflammation in neurodegenerative diseases

Neurodegenerative disorders including Alzheimer′s disease are characterized by chronic inflammation in the central nervous system. The two main glial types involved in inflammatory reactions are microglia and astrocytes. While these cells normally protect neurons by providing nutrients and growth fa...

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Bibliographic Details
Main Authors: Jocelyn M Madeira, Stephanie M Schindler, Andis Klegeris
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Neural Regeneration Research
Subjects:
tamoxifen
Src kinase
PP2
trauma
regeneration
neuroprotection
auranofin
dextromethorphan
rosiglitazone
Alzheimer′s disease
neuroinflammation
neurodegeneration
microglia
astrocytes
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=3;spage=391;epage=393;aulast=Madeira

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=3;spage=391;epage=393;aulast=Madeira

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