A novel quantification platform for point-of-care testing of circulating MicroRNAs based on allosteric spherical nanoprobe

A novel quantification platform for point-of-care testing of circulating MicroRNAs based on allosteric spherical nanoprobe

Abstract MiRNA-150, a gene regulator that has been revealed to be abnormal expression in non-small cell lung cancer (NSCLC), can be regarded as a serum indicator for diagnosis and monitoring of NSCLC. Herein, a new sort of nanoprobe, termed allosteric spherical nanoprobe, was first developed to sens...

Full description

Bibliographic Details
Main Authors: Huiyan Tian, Changjing Yuan, Yu Liu, Zhi Li, Ke Xia, Mengya Li, Fengxin Xie, Qinghai Chen, Ming Chen, Weiling Fu, Yang Zhang
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Nanobiotechnology
Subjects:
Allosteric spherical nanoprobe
Dual-hairpin
MiRNA-150
Förster resonance energy transfer (FRET)
Point-of-care testing (POCT)
Online Access:http://link.springer.com/article/10.1186/s12951-020-00717-z

Internet

http://link.springer.com/article/10.1186/s12951-020-00717-z

Similar Items