Is it worthwhile rethinking the positive experience of the last 50 years of using chondroitin sulfates against atherosclerosis?

Chondroitin sulfate (CS) and glucosamine sulfate (GS) are used in the treatment of osteoarthritis and exhibit a pronounced anti-inflammatory effect. CS/GS inhibit the NF-kB signaling cascade, which realizes the biological effects of tumor necrosis factor (TNFa). Excessive activity of NF-kB also stim...

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Main Authors:	A. M. Lila, I. Yu. Torshin, O. A. Gromova
Format:	Article
Language:	Russian
Published:	IRBIS LLC 2020-08-01
Series:	Фармакоэкономика
Subjects:	chondroitin sulfate glucosamine sulfate atherosclerosis inflammation chondroguard sustaguard artro
Online Access:	https://www.pharmacoeconomics.ru/jour/article/view/390

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spelling	doaj-03fc829ee0724eb686035b5cde11cc2d2021-07-28T13:30:41ZrusIRBIS LLCФармакоэкономика2070-49092070-49332020-08-0113218419110.17749/2070-4909/farmakoekonomika.2020.043303Is it worthwhile rethinking the positive experience of the last 50 years of using chondroitin sulfates against atherosclerosis?A. M. Lila0I. Yu. Torshin1O. A. Gromova2V.A. Nasonov Research Institute of RheumatologyFederal Research Center “Informatics and Management of the Russian Academy of Sciences“Federal Research Center “Informatics and Management of the Russian Academy of Sciences“; Moscow State UniversityChondroitin sulfate (CS) and glucosamine sulfate (GS) are used in the treatment of osteoarthritis and exhibit a pronounced anti-inflammatory effect. CS/GS inhibit the NF-kB signaling cascade, which realizes the biological effects of tumor necrosis factor (TNFa). Excessive activity of NF-kB also stimulates the development of atherosclerosis. The results of experimental and clinical studies show that inhibition of NF-kB by CS/GS will inhibit the formation and growth of atherosclerotic plaques also reducing levels of other markers of inflammation.https://www.pharmacoeconomics.ru/jour/article/view/390chondroitin sulfateglucosamine sulfateatherosclerosisinflammationchondroguardsustaguard artro
collection	DOAJ
language	Russian
format	Article
sources	DOAJ
author	A. M. Lila I. Yu. Torshin O. A. Gromova
spellingShingle	A. M. Lila I. Yu. Torshin O. A. Gromova Is it worthwhile rethinking the positive experience of the last 50 years of using chondroitin sulfates against atherosclerosis? Фармакоэкономика chondroitin sulfate glucosamine sulfate atherosclerosis inflammation chondroguard sustaguard artro
author_facet	A. M. Lila I. Yu. Torshin O. A. Gromova
author_sort	A. M. Lila
title	Is it worthwhile rethinking the positive experience of the last 50 years of using chondroitin sulfates against atherosclerosis?
title_short	Is it worthwhile rethinking the positive experience of the last 50 years of using chondroitin sulfates against atherosclerosis?
title_full	Is it worthwhile rethinking the positive experience of the last 50 years of using chondroitin sulfates against atherosclerosis?
title_fullStr	Is it worthwhile rethinking the positive experience of the last 50 years of using chondroitin sulfates against atherosclerosis?
title_full_unstemmed	Is it worthwhile rethinking the positive experience of the last 50 years of using chondroitin sulfates against atherosclerosis?
title_sort	is it worthwhile rethinking the positive experience of the last 50 years of using chondroitin sulfates against atherosclerosis?
publisher	IRBIS LLC
series	Фармакоэкономика
issn	2070-4909 2070-4933
publishDate	2020-08-01
description	Chondroitin sulfate (CS) and glucosamine sulfate (GS) are used in the treatment of osteoarthritis and exhibit a pronounced anti-inflammatory effect. CS/GS inhibit the NF-kB signaling cascade, which realizes the biological effects of tumor necrosis factor (TNFa). Excessive activity of NF-kB also stimulates the development of atherosclerosis. The results of experimental and clinical studies show that inhibition of NF-kB by CS/GS will inhibit the formation and growth of atherosclerotic plaques also reducing levels of other markers of inflammation.
topic	chondroitin sulfate glucosamine sulfate atherosclerosis inflammation chondroguard sustaguard artro
url	https://www.pharmacoeconomics.ru/jour/article/view/390
work_keys_str_mv	AT amlila isitworthwhilerethinkingthepositiveexperienceofthelast50yearsofusingchondroitinsulfatesagainstatherosclerosis AT iyutorshin isitworthwhilerethinkingthepositiveexperienceofthelast50yearsofusingchondroitinsulfatesagainstatherosclerosis AT oagromova isitworthwhilerethinkingthepositiveexperienceofthelast50yearsofusingchondroitinsulfatesagainstatherosclerosis
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Is it worthwhile rethinking the positive experience of the last 50 years of using chondroitin sulfates against atherosclerosis?

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