Indoxyl Sulfate Impairs Endothelial Progenitor Cells and Might Contribute to Vascular Dysfunction in Patients with Chronic Kidney Disease

Indoxyl Sulfate Impairs Endothelial Progenitor Cells and Might Contribute to Vascular Dysfunction in Patients with Chronic Kidney Disease

Background/Aims: Indoxyl sulfate (IS) is a protein-bound uremic toxin that accumulates in patients with chronic kidney disease (CKD). We explored the effect of IS on human early endothelial progenitor cells (EPCs) and analyzed the correlation between serum IS levels and parameters of vascular functi...

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Bibliographic Details
Main Authors: Cheng-Jui Lin, Chih-Jen Wu, Pei-Chen Wu, Chi-Feng Pan, Tuan-Jen Wang, Fang-Ju Sun, Hsuan-Liang Liu, Han-Hsiang Chen, Hung-I Yeh
Format: Article
Language:English
Published: Karger Publishers 2016-12-01
Series:Kidney & Blood Pressure Research
Subjects:
Indoxyl sulfate
Endothelial progenitor cells
Vascular function
Chronic kidney disease
Online Access:http://www.karger.com/Article/FullText/452604

Internet

http://www.karger.com/Article/FullText/452604

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