LIN28A inhibits DUSP family phosphatases and activates MAPK signaling pathway to maintain pluripotency in porcine induced pluripotent stem cells

LIN28A inhibits DUSP family phosphatases and activates MAPK signaling pathway to maintain pluripotency in porcine induced pluripotent stem cells

LIN28A, an RNA-binding protein, plays an important role in porcine induced pluripotent stem cells (piPSCs). However, the molecular mechanism underlying the function of LIN28A in the maintenance of pluripotency in piPSCs remains unclear. Here, we explored the function of LIN28A in piPSCs based on its...

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Bibliographic Details
Main Authors: Xiao-Long Wu, Zhen-Shuo Zhu, Xia Xiao, Zhe Zhou, Shuai Yu, Qiao-Yan Shen, Ju-Qing Zhang, Wei Yue, Rui Zhang, Xin He, Sha Peng, Shi-Qiang Zhang, Na Li, Ming-Zhi Liao, Jin-Lian Hua
Format: Article
Language:English
Published: Science Press, PR China 2021-05-01
Series:Zoological Research
Subjects:
lin28a
mapk
pluripotency
pipscs
dusp
Online Access:http://www.zoores.ac.cn/EN/10.24272/j.issn.2095-8137.2020.375

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