Role of an Aromatic–Aromatic Interaction in the Assembly and Trafficking of the Zebrafish Panx1a Membrane Channel

Role of an Aromatic–Aromatic Interaction in the Assembly and Trafficking of the Zebrafish Panx1a Membrane Channel

Pannexin 1 (Panx1) is a ubiquitously expressed hexameric integral membrane protein known to function as an adenosine triphosphate (ATP) release channel. Panx1 proteins exist in unglycosylated core form (Gly0). They undergo critical post-translational modifications forming the high mannose glycosylat...

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Bibliographic Details
Main Authors: Ksenia Timonina, Anna Kotova, Georg Zoidl
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomolecules
Subjects:
pannexin
integral membrane protein
structure–function
protein trafficking
n-glycosylation
co-localization
frap
fret
Online Access:https://www.mdpi.com/2218-273X/10/2/272

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