Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl) Benzoic Acid (RRL-1364) - Part-I

Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl) Benzoic Acid (RRL-1364) - Part-I

Detailed pharmacological investigations of p-N-(3, 4-methylene dioxy phenyl) benzoic acid revealed marked hypotensive action which was dose dependent and most marked in cats; it was absent in rats. Atropine could block this hypotensive action, thus suggest-ing cholinomimetic mechanism. Further studi...

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Main Authors: Dahanukar Sharadini, Sheth U
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 1978-01-01
Series:Journal of Postgraduate Medicine
Online Access:http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1978;volume=24;issue=3;spage=171;epage=176;aulast=Dahanukar
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spelling doaj-03db18647c8745de9af58113bd3b7b782020-11-25T00:01:40ZengWolters Kluwer Medknow PublicationsJournal of Postgraduate Medicine0022-38590972-28231978-01-01243171176Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl) Benzoic Acid (RRL-1364) - Part-IDahanukar SharadiniSheth UDetailed pharmacological investigations of p-N-(3, 4-methylene dioxy phenyl) benzoic acid revealed marked hypotensive action which was dose dependent and most marked in cats; it was absent in rats. Atropine could block this hypotensive action, thus suggest-ing cholinomimetic mechanism. Further studies indicated that the hypotension produced was central and possibly medullary in origin.http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1978;volume=24;issue=3;spage=171;epage=176;aulast=Dahanukar
collection DOAJ
language English
format Article
sources DOAJ
author Dahanukar Sharadini
Sheth U
spellingShingle Dahanukar Sharadini
Sheth U
Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl) Benzoic Acid (RRL-1364) - Part-I
Journal of Postgraduate Medicine
author_facet Dahanukar Sharadini
Sheth U
author_sort Dahanukar Sharadini
title Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl) Benzoic Acid (RRL-1364) - Part-I
title_short Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl) Benzoic Acid (RRL-1364) - Part-I
title_full Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl) Benzoic Acid (RRL-1364) - Part-I
title_fullStr Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl) Benzoic Acid (RRL-1364) - Part-I
title_full_unstemmed Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl) Benzoic Acid (RRL-1364) - Part-I
title_sort pharmacological studies of p, n-(3, 4-methylenedioxy phenyl) benzoic acid (rrl-1364) - part-i
publisher Wolters Kluwer Medknow Publications
series Journal of Postgraduate Medicine
issn 0022-3859
0972-2823
publishDate 1978-01-01
description Detailed pharmacological investigations of p-N-(3, 4-methylene dioxy phenyl) benzoic acid revealed marked hypotensive action which was dose dependent and most marked in cats; it was absent in rats. Atropine could block this hypotensive action, thus suggest-ing cholinomimetic mechanism. Further studies indicated that the hypotension produced was central and possibly medullary in origin.
url http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1978;volume=24;issue=3;spage=171;epage=176;aulast=Dahanukar
work_keys_str_mv AT dahanukarsharadini pharmacologicalstudiesofpn34methylenedioxyphenylbenzoicacidrrl1364parti
AT shethu pharmacologicalstudiesofpn34methylenedioxyphenylbenzoicacidrrl1364parti
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