Screening action potentials: The power of light
Action potentials reflect the concerted activity of all electrogenic constituents in the plasma membrane during the excitation of a cell. Therefore, the action potential is an integrated readout and a promising parameter to detect electrophysiological failures or modifications thereof in diagnosis a...
Main Authors: | Lars eKaestner, Peter eLipp |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2011-07-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00042/full |
Similar Items
-
Can optical recordings of membrane potential be used to screen for drug-induced action potential prolongation in single cardiac myocytes?
by: Hardy, Matthew E., et al.
Published: (2018) -
Genetically Encoded Voltage Indicators in Circulation Research
by: Lars Kaestner, et al.
Published: (2015-09-01) -
Electrophysiological Effects of the Transient Receptor Potential Melastatin 4 Channel Inhibitor (4-Chloro-2-(2-chlorophenoxy)acetamido) Benzoic Acid (CBA) in Canine Left Ventricular Cardiomyocytes
by: Csaba Dienes, et al.
Published: (2021-08-01) -
Effects of acetylcholine and noradrenalin on action potentials of isolated rabbit sinoatrial and atrial myocytes
by: Arie O. Verkerk, et al.
Published: (2012-05-01) -
A protocol combining current- and voltage-clamp provides a novel and useful three-dimensional representation of cardiac action potential
by: Massimiliano Zaniboni, et al.
Published: (2014-01-01)