How Quality Control Systems AID Sec-Dependent Protein Translocation

The evolutionarily conserved Sec machinery is responsible for transporting proteins across the cytoplasmic membrane. Protein substrates of the Sec machinery must be in an unfolded conformation in order to be translocated across (or inserted into) the cytoplasmic membrane. In bacteria, the requiremen...

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Bibliographic Details
Main Authors: Chen Jiang, Max Wynne, Damon Huber
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
Sec
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.669376/full