Multicomponent Biginelli's synthesis of 3,4-dihydropyrimidin-2(1H)-ones promoted by SnCl2.2H2O

Multicomponent Biginelli's synthesis of 3,4-dihydropyrimidin-2(1H)-ones promoted by SnCl2.2H2O

The ability of SnCl2.2H2O as catalyst to promote the Biginelli three-component condensation reaction from a diversity of aromatic aldehydes, ethyl acetoacetate and urea or thiourea is described. The reaction was carried out in acetonitrile or ethanol as solvents in neutral media and represents an im...

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Bibliographic Details
Main Authors:	Russowsky Dennis, Lopes Fabrício A., Silva Victor S. S. da, Canto Karen F. S., D'Oca Marcelo G. Montes, Godoi Marla N.
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Química 2004-01-01
Series:	Journal of the Brazilian Chemical Society
Subjects:	Biginelli reaction multicomponent reaction dihydropyrimidinones tin(II) chloride hydrate Lewis acid
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532004000200002

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