Ameliorative Effect of Curcumin-Encapsulated Hyaluronic Acid–PLA Nanoparticles on Thioacetamide-Induced Murine Hepatic Fibrosis

Ameliorative Effect of Curcumin-Encapsulated Hyaluronic Acid–PLA Nanoparticles on Thioacetamide-Induced Murine Hepatic Fibrosis

In this study, we developed curcumin-encapsulated hyaluronic acid–polylactide nanoparticles (CEHPNPs) to be used for liver fibrosis amelioration. CD44, the hyaluronic acid (HA) receptor, is upregulated on the surface of cancer cells and on activated hepatic stellate cells (aHSCs) rather than normal...

Full description

Bibliographic Details
Main Authors:	Yu-Nong Chen, Shih-Lan Hsu, Ming-Yuan Liao, Yi-Ting Liu, Chien-Hung Lai, Ji-Feng Chen, Mai-Huong Thi Nguyen, Yung-Hsiang Su, Shang-Ting Chen, Li-Chen Wu
Format:	Article
Language:	English
Published:	MDPI AG 2016-12-01
Series:	International Journal of Environmental Research and Public Health
Subjects:	hyaluronic acid curcumin nanoparticle hepatic stellate cells liver fibrosis
Online Access:	http://www.mdpi.com/1660-4601/14/1/11

Similar Items

Degree-based topological indices and polynomials of hyaluronic acid-curcumin conjugates
by: Parvez Ali, et al.
Published: (2020-09-01)

Curcumin/Usnic Acid-Loaded Electrospun Nanofibers Based on Hyaluronic Acid
by: Petr Snetkov, et al.
Published: (2020-08-01)

“Nanomaterials of curcumin-hyaluronic acid”: their various methods of formulations, clinical and therapeutic applications, present gap, and future directions
by: Tanzeel Rehman Charan, et al.
Published: (2021-06-01)

Curcumin- and Cyclopamine-Loaded Liposomes to Enhance Therapeutic Efficacy Against Hepatic Fibrosis
by: Zhang T, et al.
Published: (2020-12-01)

Dual targeting curcumin loaded alendronate-hyaluronan- octadecanoic acid micelles for improving osteosarcoma therapy
by: Xi Y, et al.
Published: (2019-08-01)

Self-Assembled Thermoresponsive Nanogel from Grafted Hyaluronic Acid as a Biocompatible Delivery Platform for Curcumin with Enhanced Drug Loading and Biological Activities
by: Jittima Amie Luckanagul, et al.
Published: (2021-01-01)

Low Dose Curcumin Administered in Hyaluronic Acid-Based Nanocapsules Induces Hypotensive Effect in Hypertensive Rats
by: Czyzynska-Cichon I, et al.
Published: (2021-02-01)

Effect of curcumin on the proliferation and apoptosis of hepatic stellate cells
by: J.C. Shu, et al.
Published: (2009-12-01)

Abrogation of ALK5 in hepatic stellate cells decreases hepatic fibrosis and ameliorates liver damage in mice following treatment with thioacetamide
by: Somyoth Sridurongrit, et al.
Published: (2018-04-01)

Inhibition by curcumin of multiple sites of the transforming growth factor-beta1 signalling pathway ameliorates the progression of liver fibrosis induced by carbon tetrachloride in rats
by: Yao Qun-yan, et al.
Published: (2012-09-01)

Evaluating the effect of curcumin on Thioacetamide -induced liver in maturemale rats
by: Solmaz Shahsavan, et al.
Published: (2018-06-01)

Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications
by: Chen Y, et al.
Published: (2020-05-01)

Preparation of curcumin-loaded nanoparticles and determination of the antioxidant potential of curcumin after encapsulation
by: Rosana Aparecida da Silva-Buzanello, et al.

Curcumin encapsulation and protection based on lysozyme nanoparticles
by: Jilai Cui, et al.
Published: (2019-08-01)

Folate-Targeted Curcumin-Encapsulated Micellar Nanosystem for Chemotherapy and Curcumin-Mediated Photodynamic Therapy
by: Yun Hsuan Lin, et al.
Published: (2020-10-01)

Photocuring Hyaluronic Acid/Silk Fibroin Hydrogel Containing Curcumin Loaded CHITOSAN Nanoparticles for the Treatment of MG-63 Cells and ME3T3-E1 Cells
by: Qingwen Yu, et al.
Published: (2021-07-01)

Preparation, Characterization and Properties of Porous PLA/PEG/Curcumin Composite Nanofibers for Antibacterial Application
by: Feifei Wang, et al.
Published: (2019-04-01)

Adjunct Therapy with Curcumin for the Treatment of Malaria : Studies in a Murine Model
by: Dende, Chaitanya
Published: (2018)

Silica Nanoparticles Loaded with Curcumin—Encapsulation Efficiency
by: Cătălin Mihăescu, et al.
Published: (2020-11-01)

Encapsulation of curcumin into layered double hydroxides
by: Supun Samindra Kamkanam M., et al.
Published: (2014-12-01)

Effect of diethanolamine on testicular steroidogenesis and its amelioration by curcumin
by: Sneha Panchal, et al.
Published: (2016-04-01)

Anti-adhesive effect of hyaluronate in a rabbit laminectomy model
by: Jian-Ming Chen, et al.
Published: (2014-08-01)

Antiplasmodial Activity and Toxicological Assessment of Curcumin PLGA-Encapsulated Nanoparticles
by: Zulaikha A. Busari, et al.
Published: (2017-09-01)

Potent effects of dioscin against thioacetamide-induced liver fibrosis through attenuating oxidative stress in turn inhibiting inflammation, TGF-β/Smad and MAPK signaling pathways
by: Xiaoling Zhang, et al.
Published: (2015-06-01)

Curcumin analog A13 alleviates oxidative stress by activating Nrf2/ARE pathway and ameliorates fibrosis in the myocardium of high-fat-diet and streptozotocin-induced diabetic rats
by: Lanting Xiang, et al.
Published: (2020-01-01)

Immunomodulatory Role of B Lymphocytes and Hyaluronic Acid in a Murine Model of Allergic Asthma
by: Ghosh, Sumit
Published: (2017)

The Effects of Kefir on Thioacetamide Induced Hepatic Fibrosis in Murine Model
by: Jie-Yu Chen, et al.
Published: (2014)

Liposomes Loaded with Everolimus and Coated with Hyaluronic Acid: A Promising Approach for Lung Fibrosis
by: Laura Pandolfi, et al.
Published: (2021-07-01)

Serum hyaluronic acid as a noninvasive marker of hepatic fibrosis in chronic hepatitis B
by: Geramizadeh Bita, et al.
Published: (2008-01-01)

Microfluidic manufacturing of different niosomes nanoparticles for curcumin encapsulation: Physical characteristics, encapsulation efficacy, and drug release
by: Mohammad A. Obeid, et al.
Published: (2019-09-01)

Potential applications of curcumin and curcumin nanoparticles: from traditional therapeutics to modern nanomedicine
by: Rai Mahendra, et al.
Published: (2015-04-01)

Hyaluronic Acid and Periodontitis
by: Sujith Sukumar, et al.
Published: (2007-01-01)

Hyaluronic acid-coated polymeric micelles with hydrogen peroxide scavenging to encapsulate statins for alleviating atherosclerosis
by: Dan Mu, et al.
Published: (2020-12-01)

Enhancement of Biological and Pharmacological Properties of an Encapsulated Polyphenol: Curcumin
by: Bwalya Angel Witika, et al.
Published: (2021-07-01)

Curcumin effect on Bleomycin-induced pulmonary fibrosis in Mus musculus
by: Annisa Rahmi, et al.
Published: (2015-06-01)

Curcumin Ameliorates Aflatoxin-Induced Changes in Caput and Cauda Epididymis of Mice
by: Ramtej Jayram Verma, et al.
Published: (2010-04-01)

The use of highmolecular-weight hyaluronic acid in the treatment of osteoarthritis
by: S. G. Anikin
Published: (2017-03-01)

Encapsulation of Curcumin in Persian Gum Nanoparticles: An Assessment of Physicochemical, Sensory, and Nutritional Properties
by: Arash Ershadi, et al.
Published: (2021-07-01)

Synergistic effects of liposomes encapsulating atorvastatin calcium and curcumin and targeting dysfunctional endothelial cells in reducing atherosclerosis
by: Li X, et al.
Published: (2019-01-01)

Knee Viscosupplementation: Cost-Effectiveness Analysis between Stabilized Hyaluronic Acid in a Single Injection versus Five Injections of Standard Hyaluronic Acid
by: Francisco J. Estades-Rubio, et al.
Published: (2017-03-01)