Pannexin-1 Contributes to the Apoptosis of Spinal Neurocytes in Spinal Cord Injury

Pannexin-1 Contributes to the Apoptosis of Spinal Neurocytes in Spinal Cord Injury

Currently, the role of Pannexin-1, a homomeric membrane hemichannel on the neuron cell membrane, in the development of spinal cord injury (SCI) is largely unknown. Herein, we assessed the contribution of Panx1 in the development of SCI. The SCI in vitro model was established using rat primary spinal...

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Bibliographic Details
Main Authors: Yu Huang, Jin Lin, Xuanwei Chen, Jianhua Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Physiology
Subjects:
pannexin-1 channels
spinal cord injury
apoptosis
Ca2+ influx
neurocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.656647/full

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