Circular RNA F-circEA-2a derived from EML4-ALK fusion gene promotes cell migration and invasion in non-small cell lung cancer

Circular RNA F-circEA-2a derived from EML4-ALK fusion gene promotes cell migration and invasion in non-small cell lung cancer

Abstract Oncogenic fusion gene Echinoderm Microtubule-associated protein-Like 4-Anaplastic Lymphoma Kinase (EML4-ALK) contributes to tumorigenesis of a subset of non-small cell lung cancer (NSCLC). Recently, we demonstrated that F-circEA-4a, a tumor-promoting circular RNA (circRNA) generated from th...

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Bibliographic Details
Main Authors: Shuangyan Tan, Dan Sun, Wenchen Pu, Qiheng Gou, Chenglin Guo, Youling Gong, Jiao Li, Yu-Quan Wei, Lunxu Liu, Yun Zhao, Yong Peng
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Molecular Cancer
Subjects:
Non-small cell lung cancer
EML4-ALK
Circular RNA
Cell migration/invasion
Online Access:http://link.springer.com/article/10.1186/s12943-018-0887-9

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