Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response

Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response

Summary: Aberrant macrophage activation during intracellular infection generates immunopathologies that can cause severe human morbidity. A better understanding of immune subversion strategies and macrophage phenotypic and functional responses is necessary to design host-directed intervention strate...

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Bibliographic Details
Main Authors: Hervé Lecoeur, Eric Prina, Thibault Rosazza, Kossiwa Kokou, Paya N’Diaye, Nathalie Aulner, Hugo Varet, Giovanni Bussotti, Yue Xing, Geneviève Milon, Robert Weil, Guangxun Meng, Gerald F. Späth
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720300450

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