Current approaches to osteoarthritis phenotyping

Osteoarthritis (OA) is currently considered as a heterogeneous disease that can be represented by different subtypes. It is the study of OA phenotypes that is one of the strategic areas for the development of researches on this nosological entity, which will further allow a personified approach to p...

Full description

Bibliographic Details
Main Authors:	A. M. Lila, L. I. Alekseeva, K. A. Telyshev
Format:	Article
Language:	Russian
Published:	IMA-PRESS LLC 2019-05-01
Series:	Современная ревматология
Subjects:	osteoarthritis approaches to phenotyping phenotypes personalized therapy
Online Access:	https://mrj.ima-press.net/mrj/article/view/904

id	doaj-039d499fb6d24e8e8c205a11b55f9832
record_format	Article
spelling	doaj-039d499fb6d24e8e8c205a11b55f98322021-07-29T09:00:12ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2019-05-011324810.14412/1996-7012-2019-2-4-82161Current approaches to osteoarthritis phenotypingA. M. Lila0L. I. Alekseeva1K. A. Telyshev2V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyOsteoarthritis (OA) is currently considered as a heterogeneous disease that can be represented by different subtypes. It is the study of OA phenotypes that is one of the strategic areas for the development of researches on this nosological entity, which will further allow a personified approach to patient therapy and ensure the rational use of financial resources of health care.The paper describes in detail the current researches on this issue. It discusses attempts to identify different OA types according to demographic data (age, race, gender, etc.), comorbidity (including depression), nature of pain (intensity, pathophysiological mechanisms of its development), biochemical markers, genetic and biomechanical predictors, hormonal status in patients, and structural changes detected by ultrasound, magnetic resonance imaging, and computed tomography, etc.https://mrj.ima-press.net/mrj/article/view/904osteoarthritisapproaches to phenotypingphenotypespersonalized therapy
collection	DOAJ
language	Russian
format	Article
sources	DOAJ
author	A. M. Lila L. I. Alekseeva K. A. Telyshev
spellingShingle	A. M. Lila L. I. Alekseeva K. A. Telyshev Current approaches to osteoarthritis phenotyping Современная ревматология osteoarthritis approaches to phenotyping phenotypes personalized therapy
author_facet	A. M. Lila L. I. Alekseeva K. A. Telyshev
author_sort	A. M. Lila
title	Current approaches to osteoarthritis phenotyping
title_short	Current approaches to osteoarthritis phenotyping
title_full	Current approaches to osteoarthritis phenotyping
title_fullStr	Current approaches to osteoarthritis phenotyping
title_full_unstemmed	Current approaches to osteoarthritis phenotyping
title_sort	current approaches to osteoarthritis phenotyping
publisher	IMA-PRESS LLC
series	Современная ревматология
issn	1996-7012 2310-158X
publishDate	2019-05-01
description	Osteoarthritis (OA) is currently considered as a heterogeneous disease that can be represented by different subtypes. It is the study of OA phenotypes that is one of the strategic areas for the development of researches on this nosological entity, which will further allow a personified approach to patient therapy and ensure the rational use of financial resources of health care.The paper describes in detail the current researches on this issue. It discusses attempts to identify different OA types according to demographic data (age, race, gender, etc.), comorbidity (including depression), nature of pain (intensity, pathophysiological mechanisms of its development), biochemical markers, genetic and biomechanical predictors, hormonal status in patients, and structural changes detected by ultrasound, magnetic resonance imaging, and computed tomography, etc.
topic	osteoarthritis approaches to phenotyping phenotypes personalized therapy
url	https://mrj.ima-press.net/mrj/article/view/904
work_keys_str_mv	AT amlila currentapproachestoosteoarthritisphenotyping AT lialekseeva currentapproachestoosteoarthritisphenotyping AT katelyshev currentapproachestoosteoarthritisphenotyping
_version_	1721250233246023680

Current approaches to osteoarthritis phenotyping

Similar Items