Triadimefon Disrupts Working Memory in the Matching-to-Position Task

Triadimefon Disrupts Working Memory in the Matching-to-Position Task

Triadimefon (TDF) is a fungicide which has psychostimulant properties similar to cocaine and amphetamine. Past studies with psychostimulants suggests that acute exposure leads to disruptions in working memory. In this study, we examined the effects of TDF exposure (relative to corn oil control) on p...

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Main Authors: John M. Holden, Ethan Hemmelman, Rowan McGlasson, Zaria Smith, Ashley Ruhland, Erin Hoover
Format: Article
Language:English
Published: SAGE Publishing 2018-10-01
Series:SAGE Open
Online Access:https://doi.org/10.1177/2158244018805798
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spelling doaj-039a347ed495463eb6cad220d8cf71422020-11-25T03:24:44ZengSAGE PublishingSAGE Open2158-24402018-10-01810.1177/2158244018805798Triadimefon Disrupts Working Memory in the Matching-to-Position TaskJohn M. Holden0Ethan Hemmelman1Rowan McGlasson2Zaria Smith3Ashley Ruhland4Erin Hoover5Winona State University, MN, USAWinona State University, MN, USAWinona State University, MN, USAWinona State University, MN, USAWinona State University, MN, USAWinona State University, MN, USATriadimefon (TDF) is a fungicide which has psychostimulant properties similar to cocaine and amphetamine. Past studies with psychostimulants suggests that acute exposure leads to disruptions in working memory. In this study, we examined the effects of TDF exposure (relative to corn oil control) on performance in the delayed matching-to-position task in two separate studies using Sprague-Dawley male rats. In both studies, TDF exposure led to significantly poorer performance across delays. TDF shows similar properties to cocaine and amphetamine in terms of disrupting working memory.https://doi.org/10.1177/2158244018805798
collection DOAJ
language English
format Article
sources DOAJ
author John M. Holden
Ethan Hemmelman
Rowan McGlasson
Zaria Smith
Ashley Ruhland
Erin Hoover
spellingShingle John M. Holden
Ethan Hemmelman
Rowan McGlasson
Zaria Smith
Ashley Ruhland
Erin Hoover
Triadimefon Disrupts Working Memory in the Matching-to-Position Task
SAGE Open
author_facet John M. Holden
Ethan Hemmelman
Rowan McGlasson
Zaria Smith
Ashley Ruhland
Erin Hoover
author_sort John M. Holden
title Triadimefon Disrupts Working Memory in the Matching-to-Position Task
title_short Triadimefon Disrupts Working Memory in the Matching-to-Position Task
title_full Triadimefon Disrupts Working Memory in the Matching-to-Position Task
title_fullStr Triadimefon Disrupts Working Memory in the Matching-to-Position Task
title_full_unstemmed Triadimefon Disrupts Working Memory in the Matching-to-Position Task
title_sort triadimefon disrupts working memory in the matching-to-position task
publisher SAGE Publishing
series SAGE Open
issn 2158-2440
publishDate 2018-10-01
description Triadimefon (TDF) is a fungicide which has psychostimulant properties similar to cocaine and amphetamine. Past studies with psychostimulants suggests that acute exposure leads to disruptions in working memory. In this study, we examined the effects of TDF exposure (relative to corn oil control) on performance in the delayed matching-to-position task in two separate studies using Sprague-Dawley male rats. In both studies, TDF exposure led to significantly poorer performance across delays. TDF shows similar properties to cocaine and amphetamine in terms of disrupting working memory.
url https://doi.org/10.1177/2158244018805798
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AT zariasmith triadimefondisruptsworkingmemoryinthematchingtopositiontask
AT ashleyruhland triadimefondisruptsworkingmemoryinthematchingtopositiontask
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