Loss of Sphingosine Kinase Alters Life History Traits and Locomotor Function in Caenorhabditis elegans

Loss of Sphingosine Kinase Alters Life History Traits and Locomotor Function in Caenorhabditis elegans

Sphingolipid metabolism is important to balance the abundance of bioactive lipid molecules involved in cell signaling, neuronal function, and survival. Specifically, the sphingolipid sphingosine mediates cell death signaling, whereas its phosphorylated form, sphingosine-1-phosphate (S1P), mediates c...

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Bibliographic Details
Main Authors:	Jason P. Chan, Jaylene Brown, Brandon Hark, Abby Nolan, Dustin Servello, Hannah Hrobuchak, Trisha A. Staab
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-09-01
Series:	Frontiers in Genetics
Subjects:	sphingosine kinase sphingolipids health span C. elegans life history traits aging
Online Access:	http://journal.frontiersin.org/article/10.3389/fgene.2017.00132/full

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