Ultrasensitive Detection of Pb2+ Based on a DNAzyme and Digital PCR

In this study, an ultrasensitive detection method for aqueous Pb2+ based on digital polymerase chain reaction (dPCR) technology and a Pb2+-dependent DNAzyme was developed. In the presence of Pb2+, the Gr-5 DNAzyme was activated and catalyzed the hydrolytic cleavage of the substrate strand, resulting...

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Bibliographic Details
Main Authors: Tao Zhang, Cong Liu, Wuping Zhou, Keming Jiang, Chenyu Yin, Zhiqiang Zhang, Haiwen Li
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2019/3528345