Engineering Liver Tissues under the Kidney Capsule Site Provides Therapeutic Effects to Hemophilia B Mice

Engineering Liver Tissues under the Kidney Capsule Site Provides Therapeutic Effects to Hemophilia B Mice

Recent advances in liver tissue engineering have encouraged further investigation into the evaluation of therapeutic benefits based on animal disease models. In the present study, liver tissues were engineered in coagulation factor IX knockout (FIX-KO) mice, a mouse model of hemophilia B, to determi...

Full description

Bibliographic Details
Main Authors:	Kazuo Ohashi M.D., Ph.D., Kohei Tatsum, Rie Utoh, Soichi Takagi, Midori Shima, Teruo Okano
Format:	Article
Language:	English
Published:	SAGE Publishing 2010-06-01
Series:	Cell Transplantation
Online Access:	https://doi.org/10.3727/096368910X508924

Similar Items

Cell Shape Regulation Based on Hepatocyte Sheet Engineering Technologies
by: Soichi Takagi, et al.
Published: (2012-03-01)

A novel cell-sheet technology that achieves durable factor VIII delivery in a mouse model of hemophilia A.
by: Kohei Tatsumi, et al.
Published: (2013-01-01)

Hepatocyte Transplantation through the Hepatic Vein: A New Route of Cell Transplantation to the Liver
by: Yuichiro Goto, et al.
Published: (2011-09-01)

Liver Tissue Engineering Utilizing Hepatocytes Propagated in Mouse Livers in Vivo
by: Kazuo Ohashi M.D., Ph.D., et al.
Published: (2012-03-01)

Therapeutic approaches for treating hemophilia A using embryonic stem cells
by: Shogo Kasuda, et al.
Published: (2016-06-01)

Bispecific Antibodies and Advances in Non–Gene Therapy Options in Hemophilia
by: Midori Shima
Published: (2020-05-01)

Transplantation of Murine Bone Marrow Stromal Cells under the Kidney Capsule to Secrete Coagulation Factor VIII
by: Taekeun Oh, et al.
Published: (2006-08-01)

Human Hepatocyte Propagation System in the Mouse Livers: Functional Maintenance of the Production of Coagulation and Anticoagulation Factors
by: Kohei Tatsumi, et al.
Published: (2012-03-01)

Stability and Repeat Regeneration Potential of the Engineered Liver Tissues under the Kidney Capsule in Mice
by: Kazuo Ohashi M.D., Ph.D., et al.
Published: (2005-10-01)

The liver surface as a favorable site for islet cell sheet transplantation in type 1 diabetes model mice
by: Izumi Fujita, et al.
Published: (2018-06-01)

Comments to: An Evaluation of Hemostatic Abnormalities in Patients With Hemophilia by APTT Waveform, Peak Heights of APTT Waveform Are Useful for Diagnosing Hemophilia or Inhibitor
by: Takeshi Matsumoto MD, PhD, et al.
Published: (2019-01-01)

Men, Masculinities, and Hemophilia
by: Laszlo Kalmar RN, MSN, et al.
Published: (2016-11-01)

Diagnostic Values of Inflammatory and Angiogenic Factors for Acute Joint Bleeding in Patients With Severe Hemophilia A
by: Huijuan Xu PhD, et al.
Published: (2020-01-01)

Joint Bleeding Tendencies in Adult Patients With Hemophilia: It’s Not All Pharmacokinetics
by: Jenny Y. Zhou MD, et al.
Published: (2019-07-01)

Consensus recommendations for the diagnosis and treatment of acquired hemophilia A
by: Shima Midori, et al.
Published: (2010-06-01)

Differences in Major Bleeding Events Between Patients With Severe Hemophilia A and Hemophilia B: A Nationwide, Population-Based Cohort Study
by: Ming-Yang Shih MD, et al.
Published: (2019-12-01)

Epidemiological Profile of Hemophilia in Baghdad-Iraq
by: Kamal Abdul Razzaq Kadhim MBChB, et al.
Published: (2019-05-01)

Characterization of the Capsule Surrounding Smooth and Textured Tissue Expanders and Correlation with Contracture
by: Erika Kuriyama, MD, et al.
Published: (2017-07-01)

Hemophilia
Published: (2009-03-01)

Hemophilia
Published: (2012)

Safety, Immunogenicity, and Hemostatic Efficacy of Nonacog Gamma in Patients With Severe or Moderately Severe Hemophilia B: A Continuation Study
by: Jerzy Windyga MD, PhD, et al.
Published: (2020-08-01)

Neonatal Gene Therapy for Hemophilia B by a Novel Adenovirus Vector Showing Reduced Leaky Expression of Viral Genes
by: Shunsuke Iizuka, et al.
Published: (2017-09-01)

PERIOPERATIVE MANAGEMENT OF PATIENTS WITH HEMOPHILIA RECEIVING FITUSIRAN, AN INVESTIGATIONAL RNAI THERAPEUTIC TARGETING ANTITHROMBIN FOR THE TREATMENT OF HEMOPHILIA
by: A.N.L. Prezotti, et al.
Published: (2020-11-01)

Hemophilia Recent Advances
Published: (2019)

Successful Endoscopic Injection Sclerotherapy of High-Risk Gastroesophageal Varices in a Cirrhotic Patient with Hemophilia A
by: Kohei Fukumoto, et al.
Published: (2010-01-01)

Comparative evaluation of the safety and efficacy of recombinant FVIII in severe hemophilia A patients
by: Hassan Abolghasemi, MD, et al.
Published: (2018-06-01)

Osteoporosis and Hemophilia
by: A.S. Kalis, et al.
Published: (2012-08-01)

Hemophilia of orbit
by: Gunaseelan Karunanithi, et al.
Published: (2009-01-01)

Phase 4 Safety and Efficacy Study of Antihemophilic Factor (Recombinant) in Previously Treated Chinese Patients With Severe/Moderately Severe Hemophilia A
by: Yongqiang Zhao PhD, et al.
Published: (2021-02-01)

Perceptions of Men With Moderate to Severe Hemophilia Regarding the Management of Their Chronic Disorder and Utilization of Community-Based Support
by: Erik B. Rolstad MSW, PhD
Published: (2015-11-01)

Knowledge about hemophilia among teachers of patients with hemophilia in Indonesia
by: Max Frans Jozef Mantik, et al.
Published: (2020-09-01)

Hemophilia and HIV-infected Hemophilia Patients’Illness Experiences in Taiwan
by: Fu-Mei Chou, et al.
Published: (2005)

Alterations of T cell receptor Vβ repertoire of CD8 T lymphocytes in immune tolerance induction in two hemophilia A patients with inhibitors
by: Sakurai Yoshihiko, et al.
Published: (2011-01-01)

Emicizumab in the treatment of hemophilia A
by: Tijanić Ivan R., et al.
Published: (2020-01-01)

Superficial Siderosis of the Central Nervous System associated with Hemophilia A: A case report
by: Quentin Thomas, MS, et al.
Published: (2021-03-01)

Navigating Speed Bumps on the Innovation Highway in Hemophilia Therapeutics
by: Donna M. DiMichele
Published: (2018-10-01)

Optimization of prophylaxis for hemophilia A.
by: Robert D Herbert, et al.
Published: (2018-01-01)

Living with a “hemophilia‐free mind” – The new ambition of hemophilia care?
by: Evelien Krumb, et al.
Published: (2021-07-01)

Societal impact for patients with psoriasis: A nationwide Swedish register studyCapsule Summary
by: Henrike Häbel, PhD, et al.
Published: (2021-06-01)

Repair of Rotator Cuff Tear With Delamination: Independent Repairs of the Infraspinatus and Articular Capsule
by: Tomoyuki Mochizuki, M.D., Ph.D., et al.
Published: (2016-10-01)