Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development.

Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development.

An increasing amount of evidence indicates that developmental programs are tightly regulated by the complex interplay between signaling pathways, as well as transcriptional and epigenetic processes. Here, we have uncovered coordination between transcriptional and morphogen cues to specify Merkel cel...

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Bibliographic Details
Main Authors: Carolina N Perdigoto, Katherine L Dauber, Carmit Bar, Pai-Chi Tsai, Victor J Valdes, Idan Cohen, Francis J Santoriello, Dejian Zhao, Deyou Zheng, Ya-Chieh Hsu, Elena Ezhkova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4944976?pdf=render

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