Clinical implications of cytosine deletion of exon 5 of P53 gene in non small cell lung cancer patients

Clinical implications of cytosine deletion of exon 5 of P53 gene in non small cell lung cancer patients

Aim: Lung cancer is considered to be the most common cancer in the world. In humans, about 50% or more cancers have a mutated tumor suppressor p53 gene thereby resulting in accumulation of p53 protein and losing its function to activate the target genes that regulate the cell cycle and apoptosis. Ex...

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Bibliographic Details
Main Authors: Rashid Mir, Mirza Masroor, Jamsheed Javid, Imtiyaz Ahamad, Shazia Farooq, Prasant Yadav, Mariyam Zuberi, Maqbool Lone, P C Ray, Alpana Saxena
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2016-01-01
Series:South Asian Journal of Cancer
Subjects:
Nonsmall cell lung cancer, adeno-carcinoma, squamous cell carcinoma, allele specific oligonucleotide, P53 (exon5, codon168) cytosine deletion
Online Access:http://journal.sajc.org/article.asp?issn=2278-330X;year=2016;volume=5;issue=1;spage=33;epage=36;aulast=Mir

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