Chemically stable inhibitors of 14-3-3 protein–protein interactions derived from BV02

Chemically stable inhibitors of 14-3-3 protein–protein interactions derived from BV02

14-3-3 are regulatory proteins that through protein–protein interactions (PPI) with numerous binding partners could be involved in several human diseases, including cancer, neurodegenerative disorders, and pathogens infections. Following our research interest in the development of 14-3-3 PPI inhibit...

Full description

Bibliographic Details
Main Authors: Leire Iralde-Lorente, Ylenia Cau, Letizia Clementi, Lorenzo Franci, Giusy Tassone, Daniela Valensin, Mattia Mori, Adriano Angelucci, Mario Chiariello, Maurizio Botta
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
14-3-3
protein–protein interaction
c-abl
leukaemia
4-aminoantipyrine
Online Access:http://dx.doi.org/10.1080/14756366.2019.1574779

Internet

http://dx.doi.org/10.1080/14756366.2019.1574779

Similar Items