Depression treatment response to ketamine: sex-specific role of interleukin-8, but not other inflammatory markers

Depression treatment response to ketamine: sex-specific role of interleukin-8, but not other inflammatory markers

Abstract Inflammation plays a role in depression pathophysiology and treatment response, with effects varying by sex and therapeutic modality. Lower levels of interleukin(IL)-8 predict depression response to antidepressant medication and to electroconvulsive therapy (ECT), although ECT effects are s...

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Bibliographic Details
Main Authors: Jennifer L. Kruse, Megha M. Vasavada, Richard Olmstead, Gerhard Hellemann, Benjamin Wade, Elizabeth C. Breen, John O. Brooks, Eliza Congdon, Randall Espinoza, Katherine L. Narr, Michael R. Irwin
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01268-z

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