Somatic mutations of isocitrate dehydrogenases 1 and 2 are prognostic and follow-up markers in patients with acute myeloid leukaemia with normal karyotype

Somatic mutations of isocitrate dehydrogenases 1 and 2 are prognostic and follow-up markers in patients with acute myeloid leukaemia with normal karyotype

Mutations in the isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) genes are frequent molecular lesions in acute myeloid leukaemia with normal karyotype (AML-NK). The effects of IDH mutations on clinical features and treatment outcome in AML-NK have been widely investigated, but only a few studies mo...

Full description

Bibliographic Details
Main Authors: Virijevic Marijana, Karan-Djurasevic Teodora, Marjanovic Irena, Tosic Natasa, Mitrovic Mirjana, Djunic Irena, Colovic Natasa, Vidovic Ana, Suvajdzic-Vukovic Nada, Tomin Dragica, Pavlovic Sonja
Format: Article
Language:English
Published: Sciendo 2016-12-01
Series:Radiology and Oncology
Subjects:
idh1 mutations
idh2 mutations
acute myeloid leukaemia
normal karyotype
Online Access:https://doi.org/10.1515/raon-2016-0044

Internet

https://doi.org/10.1515/raon-2016-0044

Similar Items