Nanopore Sequencing of a Forensic STR Multiplex Reveals Loci Suitable for Single-Contributor STR Profiling

Nanopore Sequencing of a Forensic STR Multiplex Reveals Loci Suitable for Single-Contributor STR Profiling

Nanopore sequencing for forensic short tandem repeats (STR) genotyping comes with the advantages associated with massively parallel sequencing (MPS) without the need for a high up-front device cost, but genotyping is inaccurate, partially due to the occurrence of homopolymers in STR loci. The goal o...

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Bibliographic Details
Main Authors: Olivier Tytgat, Yannick Gansemans, Jana Weymaere, Kaat Rubben, Dieter Deforce, Filip Van Nieuwerburgh
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Genes
Subjects:
forensic
DNA fingerprinting
short tandem repeats
Oxford Nanopore sequencing
massively parallel sequencing
Online Access:https://www.mdpi.com/2073-4425/11/4/381

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