Neuroprotective effect of diosgenin in a mouse model of diabetic peripheral neuropathy involves the Nrf2/HO-1 pathway

Neuroprotective effect of diosgenin in a mouse model of diabetic peripheral neuropathy involves the Nrf2/HO-1 pathway

Abstract Background Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. Diosgenin is a natural steroidal saponin with a variety of beneficial effects, including antidiabetic effects, and is a raw material for the synthesis of carrier hormones. In our stu...

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Bibliographic Details
Main Authors: Jinhong Leng, Xiaohua Li, He Tian, Chang Liu, Yining Guo, Su Zhang, Yang Chu, Jian Li, Ying Wang, Ling Zhang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Diosgenin
Diabetic peripheral neuropathy
Nrf2
HO-1
Oxidative stress
Online Access:http://link.springer.com/article/10.1186/s12906-020-02930-7

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