Acute Injection of Omega-3 Triglyceride Emulsion Provides Very Similar Protection as Hypothermia in a Neonatal Mouse Model of Hypoxic-Ischemic Brain Injury

Acute Injection of Omega-3 Triglyceride Emulsion Provides Very Similar Protection as Hypothermia in a Neonatal Mouse Model of Hypoxic-Ischemic Brain Injury

Therapeutic hypothermia (HT) is a currently accepted treatment for neonatal asphyxia and is a promising strategy in adult stroke therapy. We previously reported that acute administration of docosahexaenoic acid (DHA) triglyceride emulsion (tri-DHA) protects against hypoxic-ischemic (HI) injury in ne...

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Bibliographic Details
Main Authors: Denny Joseph Manual Kollareth, Hylde Zirpoli, Vadim S. Ten, Richard J. Deckelbaum
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Neurology
Subjects:
DHA
hypothermia
hypoxic-ischemic injury
neuroprotection
omega-3 fatty acids
stroke
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.618419/full

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