Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery.

Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery.

Virus-mediated expression of defined transcription factor (TF) genes can effectively induce cellular reprogramming. However, sustained expression of the TFs often hinders pluripotent stem cell (PSC) differentiation into specific cell types, as each TF exerts its effect on PSCs for a defined period o...

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Bibliographic Details
Main Authors: Yongxin Jin, Ying Liu, Zhenpeng Li, Katherine Santostefano, Jing Shi, Xinwen Zhang, Donghai Wu, Zhihui Cheng, Weihui Wu, Naohiro Terada, Shouguang Jin, Fang Bai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5868831?pdf=render

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