SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans

SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans

Piwi-interacting RNAs (piRNAs) play essential roles in silencing repetitive elements to promote fertility in metazoans. Studies in worms, flies, and mammals reveal that piRNAs are expressed in a sex-specific manner. However, the mechanisms underlying this sex-specific regulation are unknown. Here we...

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Bibliographic Details
Main Authors: Charlotte P Choi, Rebecca J Tay, Margaret R Starostik, Suhua Feng, James J Moresco, Brooke E Montgomery, Emily Xu, Maya A Hammonds, Michael C Schatz, Taiowa A Montgomery, John R Yates III, Steven E Jacobsen, John K Kim
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
piRNA
spermatogenesis
sex determination
germline development
TRA-1
transcription
Online Access:https://elifesciences.org/articles/60681

Internet

https://elifesciences.org/articles/60681

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