Role of ALDH1A1 and HTRA2 expression in CCL2/CCR2-mediated breast cancer cell growth and invasion

Role of ALDH1A1 and HTRA2 expression in CCL2/CCR2-mediated breast cancer cell growth and invasion

Chemokines mediate immune cell trafficking during tissue development, wound healing and infection. The chemokine CCL2 is best known to regulate macrophage recruitment during wound healing, infection and inflammatory diseases. While the importance of CCL2/CCR2 signaling in macrophages during cancer p...

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Bibliographic Details
Main Authors: Qingting Hu, Megan Myers, Wei Fang, Min Yao, Gage Brummer, Justin Hawj, Curtis Smart, Cory Berkland, Nikki Cheng
Format: Article
Language:English
Published: The Company of Biologists 2019-07-01
Series:Biology Open
Subjects:
CCL2
CCR2
Breast cancer
3D culture
Cell invasion
ALDH1A1
HTRA2
Online Access:http://bio.biologists.org/content/8/7/bio040873

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