Angptl8 mediates food-driven resetting of hepatic circadian clock in mice

The circadian clock regulates rhythms of behavior and physiology and the timing of circadian rhythms in liver is influenced by food intake. Here, the authors identify the hepatokine Angptl8 as a mediator of liver clock food entrainment.

Bibliographic Details
Main Authors:	Siyu Chen, Mengyang Feng, Shiyao Zhang, Zhewen Dong, Yifan Wang, Wenxiang Zhang, Chang Liu
Format:	Article
Language:	English
Published:	Nature Publishing Group 2019-08-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-019-11513-1

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spelling	doaj-033c8e19e26e422587263c408fb3aec12021-05-11T12:12:46ZengNature Publishing GroupNature Communications2041-17232019-08-0110111610.1038/s41467-019-11513-1Angptl8 mediates food-driven resetting of hepatic circadian clock in miceSiyu Chen0Mengyang Feng1Shiyao Zhang2Zhewen Dong3Yifan Wang4Wenxiang Zhang5Chang Liu6State Key Laboratory of Natural Medicines, China Pharmaceutical UniversityState Key Laboratory of Natural Medicines, China Pharmaceutical UniversitySchool of Life Science and Technology, China Pharmaceutical UniversitySchool of Life Science and Technology, China Pharmaceutical UniversitySchool of Life Science and Technology, China Pharmaceutical UniversityState Key Laboratory of Natural Medicines, China Pharmaceutical UniversityState Key Laboratory of Natural Medicines, China Pharmaceutical UniversityThe circadian clock regulates rhythms of behavior and physiology and the timing of circadian rhythms in liver is influenced by food intake. Here, the authors identify the hepatokine Angptl8 as a mediator of liver clock food entrainment.https://doi.org/10.1038/s41467-019-11513-1
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Siyu Chen Mengyang Feng Shiyao Zhang Zhewen Dong Yifan Wang Wenxiang Zhang Chang Liu
spellingShingle	Siyu Chen Mengyang Feng Shiyao Zhang Zhewen Dong Yifan Wang Wenxiang Zhang Chang Liu Angptl8 mediates food-driven resetting of hepatic circadian clock in mice Nature Communications
author_facet	Siyu Chen Mengyang Feng Shiyao Zhang Zhewen Dong Yifan Wang Wenxiang Zhang Chang Liu
author_sort	Siyu Chen
title	Angptl8 mediates food-driven resetting of hepatic circadian clock in mice
title_short	Angptl8 mediates food-driven resetting of hepatic circadian clock in mice
title_full	Angptl8 mediates food-driven resetting of hepatic circadian clock in mice
title_fullStr	Angptl8 mediates food-driven resetting of hepatic circadian clock in mice
title_full_unstemmed	Angptl8 mediates food-driven resetting of hepatic circadian clock in mice
title_sort	angptl8 mediates food-driven resetting of hepatic circadian clock in mice
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2019-08-01
description	The circadian clock regulates rhythms of behavior and physiology and the timing of circadian rhythms in liver is influenced by food intake. Here, the authors identify the hepatokine Angptl8 as a mediator of liver clock food entrainment.
url	https://doi.org/10.1038/s41467-019-11513-1
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Angptl8 mediates food-driven resetting of hepatic circadian clock in mice

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