Clostridium difficile suppresses colonic vasoactive intestinal peptide associated with altered motility

We investigated whether Clostridium difficile toxin alters colonic tissue levels of vasoactive intestinal peptide (VIP) at the expense of changes in colonic motility in the isolated perfused rabbit left colon. Colonic inflammation was induced by the intracolonic administration of 10−8 M C. difflcile...

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Bibliographic Details
Main Authors: A. Nassif, W. E. Longo, R. Sexe, M. Stratton, J. Standeven, A. M. Vernava, D. L. Kaminski
Format: Article
Language:English
Published: Hindawi Limited 1995-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S096293519500072X

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